This manuscript reports important findings on the impact of maternal obesity on offspring metabolism. It presents solid evidence that maternal obesity induces genomic methylation alterations in ...

This manuscript reports important findings on the impact of maternal obesity on oocyte methylation and its transgenerational effects. The evidence presented to substantiate the major claims appears ...

A new collaborative study from Karolinska Institutet published in Science Advances shows that the levels of mitochondrial DNA (mtDNA) directly influence lung adenocarcinoma (LUAD) progression in mice.

A new study introduces a method to infer DNA methylation patterns in non-skeletal tissues from ancient DNA, offering insights into human evolution, particularly brain function. Using an algorithm with ...

Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial DNA (mtDNA). This condition can cause symptoms including muscle weakness ...

Controls survived longer than 5 years without evidence of melanoma recurrence or relapse. Methylation classes, distinguished by consensus clustering of 850K methylation data, were evaluated for their ...

Nov. 28, 2024 — More than a million years ago, on a hot savannah teeming with wildlife near the shore of what would someday become Lake Turkana in Kenya, two completely different species of ...