It was able to predict the efficacy of some established combination therapies for NSCLC, such as BRAF/MEK and EGFR/mTOR inhibitors, but also identified brand new recipes. For example, it suggested ...
These are the receptor tyrosine kinases (for example, EGFR, ERBB2, platelet-derived growth ... PIK3CA, Akt and mTOR). These three groups of targets are mechanistically linked because most receptor ...