The San Francisco 49ers saw their playoff chances plummet following consecutive losses to the Seattle Seahawks and Green Bay ...

"Sunday Night Football" in Week 13 sees the San Francisco 49ers taking on the Buffalo Bills. Here's the latest on a snowy ...

The Buffalo Bills (9-2) take a six-game winning streak into their contest with the San Francisco 49ers on Sunday, December 1, ...

QB Brock Purdy injured his shoulder in Week 11 against the Seattle Seahawks and wound up missing the team’s blowout Week 12 ...

Dre Greenlaw practiced for the first time this week since he tore his Achilles in the Super Bowl. Here's what head coach Kyle ...

Four NFL games on Thanksgiving and Black Friday kicked off Week 13 action, and the full schedule continues on Sunday, Dec. 1, ...

Charlotte football ended its season victorious. With the 49ers holding a 29-27 lead during the final minutes, Alabama ...

The #Bills have activated Pro Bowl LB Matt Milano off Injured Reserve and he’ll play on Sunday against the #49ers for the ...

Heavy snow is expected in Erie County, New York, this weekend, including when the AFC East-leading Bills host the 49ers for ...

The National Weather Service has extended its "lake effect snow warning" in Buffalo through Monday at 7 p.m. ET, with ...

The San Francisco 49ers (5-6) try to salvage their season against the Buffalo Bills (9-2) on Sunday Night Football. Kickoff ...

The Buffalo Bills have reactivated All-Pro linebacker Matt Milano ahead of their Week 13 match up against the San Francisco ...