The San Francisco 49ers’ dreadful season got worse in Week 13 when running backs Christian McCaffrey and Jordan Mason both ...

The San Francisco 49ers will be without their top two running backs for the remainder of the regular season after the pair of ...

With its 35-10 loss at Buffalo on Sunday night, the 49ers have now dropped three straight to sink to 5-7 on the season. The ...

After sparking the 49ers with a handful of impressive runs, Christian McCaffrey looked like himself early in the game against ...

San Francisco 49ers running back Christian McCaffrey is feared to have suffered a season-ending PCL injury vs. the Buffalo ...

Somehow Week 13 was worse than for the San Francisco 49ers than Week 12. The 49ers fell behind 21-3 at halftime and had a ...

The 49ers star running back was ruled out of Sunday Night Football after suffering a knee injury in the first half against ...

During Sunday Night Football against the Bills, Isaac Guerendo punched in his second touchdown of his rookie campaign.

San Francisco running back Christian McCaffrey was officially ruled out of the 49ers’ Sunday Night Football contest at the ...

San Francisco 49ers linebacker Fred Warner exited with cramps, but then later returned in the first half vs. the Buffalo ...

San Francisco star running back Christian McCaffrey exited the 49ers Sunday Night Football game against the Bills with a knee ...

In the first half, defensive tackle Kevin Givens exited the game with a chest injury. After entering the blue medical tent in ...