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pharmaphorum
25 分钟
MSD adds rocket fuel to Winrevair's engine in PAH
In March, Winrevair became the first FDA-approved therapy for PAH that addresses the underlying mechanism behind the disease, ...
pharmaphorum
1 小时
End looms for Cassava's simufilam in Alzheimer's disease
Cassava Sciences' troubled development of Alzheimer's disease candidate simufilam looks like it may have finally reached the ...
BioSpace
8 小时
Cassava’s Shares Plunge as Alzheimer’s Drug Fails Phase III
Cassava Sciences has revealed the late-stage clinical failure of controversial Alzheimer’s drug simulfilam. The company had ...
8 小时
Trial of Controversial Alzheimer’s Drug Halted After Disappointing Results
Cassava Sciences said that its drug did not significantly reduce cognitive decline in 1,900 people with mild to moderate ...
第一黄金网
12 小时
Simufilam 3期阿尔茨海默氏症试验未达到终点 Cassava Sciences(SAVA.US)暴跌超84%
,周一,Cassava Sciences(SAVA.US)股价暴跌,截至发稿,该股跌超84%,报4.06美元。该公司表示 ,周一,Cassava Sciences(SAVA.US)股价暴跌,截至发稿,该股跌超84%,报4.06美元。该公司表示,其simufilam治疗轻度至中度阿尔茨海默症的3期ReThink-ALZ研究的初步结果没有达到预先设定的共同主要终点、次要终点和探索性生物标志物终点。 该 ...
12 小时
Cassava announces Phase 3 ReThink-ALZ data did not meet co-primary endpoints
Cassava Sciences (SAVA) announced that the topline results from the Phase 3 ReThink-ALZ study of simufilam in mild-to-moderate AD did not meet ...
12 小时
D. Boral says Anavex Alzheimer’s approach superior to Cassava
D. Boral Capital keeps a Buy rating on Anavex Life Sciences (AVXL) with a $46 price target after Cassava Sciences’ (SAVA) Phase 3 trial for ...
NewsX
13 小时
Cassava Sciences Alzheimer’s Drug Fails, Stocks Plunge
Cassava Sciences Inc. faced a major setback as its Alzheimer's drug, simufilam, failed to meet critical endpoints in a Phase ...
Monthly Prescribing Reference
14 小时
No Significant Improvement With Simufilam in Alzheimer Disease Trial
Simufilam is an investigational oral small molecule that targets the filamin A protein. In the ReThink-ALZ study (ClinicalTrials.gov Identifier: NCT04994483 ), patients with confirmed mild or moderate ...
STAT
14 小时
Cassava Sciences and its Alzheimer’s drug are done. The damage lingers
The Cassava Sciences story ended Monday exactly as many knew it would — with the company’s experimental drug for Alzheimer’s ...
The Pharma Letter
15 小时
Cassava crashes as Alzheimer’s dream dies
Cassava Sciences, a US biotech developing a novel, investigational treatment for Alzheimer’s disease (AD) dementia, was ...
15 小时
Cassava Sciences stock plummets after Phase III Alzheimer’s fail
Following the ReThink study failure, Cassava Sciences is discontinuing the Phase III ReFocus trial and open-label study.
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