Seattle Seahawks linebacker Boye Mafe gets to Arizona Cardinals quarterback Kyler Murray for his fifth sack of season.

Jaire Alexander, Edgerrin Cooper, Brock Purdy and Nick Bosa were all ruled out Friday; 49ers LT Trent Williams joins them on ...

San Francisco 49ers left tackle Trent Williams has been sidelined for the team's Week 12 matchup vs. the Green ...

Quarterback Brandon Allen’s first start in place of an injured Brock Purdy won’t come with the luxury of having All-Pro Trent ...

This story keeps getting weirder. On Thursday, 49ers quarterback Brock Purdy apparently had a second MRI on his injured ...

The Green Bay Packers are heavy favorites for their game against the rival San Francisco 49ers on Sunday at Lambeau Field.

The Green Bay Packers won’t have to face three of the star players for the San Francisco 49ers on Sunday at Lambeau Field.

When it rains, it pours for the San Francisco 49ers. Kyle Shanahan's team hasn't been able to catch a break this season. They ...

The San Francisco 49ers are playing Brandon Allen at quarterback in Week 12 against the Green Bay Packers. The team’s ...

An injury to the blossoming passer’s throwing shoulder will keep him out in Green Bay, though no IR stint should be expected.

The San Francisco 49ers are optimistic about the status of quarterback Brock Purdy for their Week 13 clash with the Buffalo ...

The Buffalo Bills' future opponent, San Francisco 49ers quarterback Brock Purdy, may not play in their Week 13 matchup.