In a season where running backs are thriving in the NFL, the 49ers hope to get Christian McCaffrey back on track.

The San Francisco 49ers, despite careening toward the abyss of NFL mediocrity, still have a path to the postseason as they ...

The sky is falling in the Bay Area, but the San Francisco 49ers finally got some good and 'potentially significant' news. Per ...

San Francisco 49ers coach Kyle Shanahan explained why star linebacker Dre Greenlaw is participating in "mock games" during ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on “Sunday Night Football” in Week 13. The ...

The Packers are eager to parry their own jab after last year's playoff exit at the hands of what's become a familiar foe.

The 49ers walked out of the Packers loss banged up and embarrassed, but the team now got welcoming news involving Dre ...

As the weather turns colder and the leaves turn brown, it can only mean one thing: NFL football means just a little bit more.

The Kansas City Chiefs will play a rare Friday game in Week 13, hosting the Las Vegas Raiders for a special Black Friday edition of the NFL.

Why isn’t Brock Purdy playing for the 49ers against the Packers? Purdy, the star of the team’s run to Super Bowl LVIII, will ...

Depending on where a fan's allegiances lie, there may be no better follow-up in the aftermath of Super Bowl LVIII ... 49ers players if they really thought that was going to be enough to win the game.

San Francisco 49ers players and coaches discuss what it means to be apart of Super Bowl LVIII at Super Bowl Opening Night. 11-year-old reporter Jeremiah Fennell and NFL Network's Michael Robinson ...