These signals synergize to release the autoinhibitory DH-PH domain, while the histone domain fine-tunes SOS activation in response to PIP 2. External signals stimulate pathways that control ...

Genes make up the blueprints and outline the process of building every living organism. To ensure that the right genes are ...

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This work will be of high interest to a broad swathe of scientists studying native macromolecules present at low concentrations in cells. Cryo-EM single-particle analyses typically require target ...

A film set is a bustling ecosystem, and every person has a part to play in getting a project to the finish line. You may hear the terms “above the line” and “below the line” to describe ...

This interesting study presents valuable information on how human cytomegalovirus (HCMV) infection disrupts the activity of the TEAD1 transcription factor, leading to widespread chromatin alterations.

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