Senescence is the process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing cell death. Senescence can be induced by unrepaired DNA damage ...

Keywords: Prostate cancer senescence, tumor induced senescent (TIS), senescence-associated secretory phenotype (SASP), cancer senescence Important Note: All contributions to this Research Topic must ...

The concept of permanent and irreversible cell cycle arrest (senescence) was initially regarded as a defence mechanism against tumour progression. However, research has demonstrated that senescent ...

Healthcare - The exploration of peptides as bioregulatory molecules has gained considerable attention in recent years, with a ...

Background Socioeconomic status (SES) is associated with many chronic diseases, indicators of senescence and mortality. However, the changing salience of SES in the prediction of adult health is not ...

In the recent decades, there has been an increase in the aging population across the world coupled with declining birth rates and an increased lifespan of individuals. The proportion of the ...

Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.

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State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union ...

Unlike the long-living postmitotic neurons that endure DNA damage, the non-neuronal cells can go through the cell cycle and are replaceable. Due to the non-replicative status of differentiated neurons ...