The 49ers have revealed their latest injury report from Wednesday’s practice before their Sunday Night Football tilt against ...

Brock Purdy will travel with the San Francisco 49ers for their Week 12 game against the Green Bay Packers, but it will be ...

The Rams will be able to keep tabs on their divisional foes, if they want, before Sunday night’s showdown against ...

The Buffalo Bills are returning from their bye week to face the San Francisco 49ers. Before the bye week, the Bills claimed a ...

The San Francisco 49ers received important Brock Purdy, Trent Williams and Nick Bosa injury updates on Wednesday.

The Packers took care of business against the shorthanded 49ers Sunday, but the celebration is only temporary.

The San Francisco 49ers will hold three full practices this week as they prepare for their Week 12 matchup against the Green Bay Packers. Head coach Kyle Shanahan, defensive coordinator Nick Sorensen ...

San Francisco 49ers running back Christian McCaffrey (23) fumbles the ball against the Green Bay Packers during their ...

Getting blown out at Green Bay following another squandered late lead the previous week against Seattle has quickly turned ...

Saquon Barkley and Derrick Henry combined for 395 yards rushing on back-to-back nights at SoFi Stadium as the dynamic playmakers keep proving that investing in running backs can pay off in the right ...

Sunday's showdown at Lambeau Field may not come down to which side has the better team, but rather which squad better handles ...