Division of Genetics, Department of Medicine, Brigham and Women’s Hospital, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United ...
Epigenetics and epigenomics represent two burgeoning fields at the forefront of modern biological inquiry. Epigenetics investigates heritable changes in gene expression that occur without any ...
This work will be of high interest to a broad swathe of scientists studying native macromolecules present at low concentrations in cells. Cryo-EM single-particle analyses typically require target ...
These signals synergize to release the autoinhibitory DH-PH domain, while the histone domain fine-tunes ... pathways is starting to reveal the molecular basis for these complex control mechanisms.