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IPHASE/汇智和源 药物代谢酶CYP450 IC50抑制体外评估模型解析
在临床应用中患者经常会同时使用多种药物,这些药物可能会产生药物-药物相互作用(Drug-drug interaction, DDI),最终导致严重不良反应或减弱治疗效果,因此,有必要对DDI发生的可能及其影响程度和严重性进行科学评估。对此,国家药监局药审中心发布的《药物 ...
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