Epigenetics and epigenomics represent two burgeoning fields at the forefront of modern biological inquiry. Epigenetics investigates heritable changes in gene expression that occur without any ...
This interesting study presents valuable information on how human cytomegalovirus (HCMV) infection disrupts the activity of the TEAD1 transcription factor, leading to widespread chromatin alterations.
Nuclear condensates play many important roles in chromatin functions, but how cells regulate their nucleation and growth within the complex nuclear environment is not well understood. Here, we report ...
Eisbach Bio GmbH, a pioneering precision oncology company, is pleased to announce the receipt of a Texas Therapeutics Company Award from the Cancer Prevention and Research Institute of Texas (CPRIT).
Chromatin structure describes the physical structure of chromatin within the eukaryotic nucleus and how structure affects chromatin processes such as transcription. The repeating unit of chromatin ...
However, the temporal relationships and functional modulations between these PCNA-binding proteins are unclear. Here, we developed a strategy to purify endogenous PCNA-containing complexes from native ...
Chromatin is a flexibly joined chain of nucleosomes that exists inside the nucleus of eukaryotic cells and has been described as a 'bead on a string'. Chromatin organization strengthens DNA for ...
New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...