This interesting study presents valuable information on how human cytomegalovirus (HCMV) infection disrupts the activity of the TEAD1 transcription factor, leading to widespread chromatin alterations.

Nuclear condensates play many important roles in chromatin functions, but how cells regulate their nucleation and growth within the complex nuclear environment is not well understood. Here, we report ...

Chromatin is a flexibly joined chain of nucleosomes that exists inside the nucleus of eukaryotic cells and has been described as a 'bead on a string'. Chromatin organization strengthens DNA for ...

Chromatin structure describes the physical structure of chromatin within the eukaryotic nucleus and how structure affects chromatin processes such as transcription. The repeating unit of chromatin ...

The eukaryotic genome is organized in the form of a highly compact nucleoprotein complex, the chromatin. Nucleosome, the basic unit of chromatin, consists of ~147 bp of DNA wrapped 1.65 times around a ...

In a recent study published in Nature Cancer, researchers explore treatment resistance and relapse in T-cell acute ...

Epigenetics and epigenomics represent two burgeoning fields at the forefront of modern biological inquiry. Epigenetics investigates heritable changes in gene expression that occur without any ...

Vilon, a bioregulatory peptide, has captured the attention of scientists for its unique characteristics and intriguing ...

Researchers unveil a comprehensive multi-omics atlas of ovarian aging, highlighting coordinated gene expression changes, mTOR ...

Early development of an embryo is solely supported by maternally deposited RNAs and proteins until its own genome is activated through a process called zygotic genome activation (ZGA). Recent work by ...

A new study led by Harvard Medical School researchers shed new light on how even a single defective copy of the ...

This research investigates the molecular mechanisms by which SMAD2/3-SMYD2 and developmental transcription factors cooperate ...