Nuclear condensates play many important roles in chromatin functions, but how cells regulate their nucleation and growth within the complex nuclear environment is not well understood. Here, we report ...
The eukaryotic genome is organized in the form of a highly compact nucleoprotein complex, the chromatin. Nucleosome, the basic unit of chromatin, consists of ~147 bp of DNA wrapped 1.65 times around a ...
Epigenetics and epigenomics represent two burgeoning fields at the forefront of modern biological inquiry. Epigenetics investigates heritable changes in gene expression that occur without any ...
Chromatin structure describes the physical structure of chromatin within the eukaryotic nucleus and how structure affects chromatin processes such as transcription. The repeating unit of chromatin ...
Eisbach Bio's innovative approach focuses on exploiting the unique genetic vulnerabilities present in solid tumors with deficiencies in certain DNA repair pathways. Eisbach’s proprietary ALLOS ...
Given their non-migratory nature within the mineralized matrix, their unique dendrites are crucial for cell-to-cell communication in response to both intracellular and extracellular stimuli, such as ...