Flow cytometry showed monoclonal plasma cells positive for CD38, CD138, CD81, CD28, with κ-light chain restriction (figure 5). These cells were negative for CD19, CD20, CD27 and CD117. Serological ...
This important study shows that soluble uric acid is an endogenous inhibitor of CD38, a regulator of inflammatory responses. The convincing evidence draws both on biochemical analyses and in vivo ...
The Phase I multi-centre and open-label study is structured in two parts. It is anticipated to enrol around 100 subjects with advanced cluster of differentiation 138 (CD138)-expressing cancers. It ...