San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there ...

There is a High Risk of Weather Impact (ROWI) for the NFL's Sunday Night Football matchup between the San Francisco 49ers ...

Buffalo Bills quarterback Josh Allen and coach Sean McDermott reacted to forecasts of a snow game against the San Francisco ...

The banged-up San Francisco 49ers received some positive news on Wednesday. Per ESPN's Nick Wagoner, 49ers head coach Kyle ...

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco ...

Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...

The highly anticipated Buffalo Bills clash against the San Francisco 49ers, scheduled for Sunday at Highmark Stadium, faces ...

The Bills will take on the San Francisco 49ers on Sunday night at Highmark Stadium in Orchard Park. Lake-effect snow bands ...

San Francisco has been up and down all season, but the Super Bowl hangover appears to be happening after the 49ers got ...

San Francisco 49ers quarterback Brock Purdy will miss Sunday’s game against the Green Bay Packers with a sore throwing ...

San Francisco 49ers left tackle Trent Williams won’t be available to protect Brandon Allen’s blind side Sunday as the veteran ...

Newsweek's NFL betting expert provides the best NFL player prop picks for 49ers vs. Packers on Sunday afternoon.