In a season where running backs are thriving in the NFL, the 49ers hope to get Christian McCaffrey back on track.

San Francisco 49ers coach Kyle Shanahan explained why star linebacker Dre Greenlaw is participating in "mock games" during ...

Here are five players who could change the game for the 49ers when they host the two-time ... particularly in the second half ...

San Francisco 49ers players and coaches discuss what it means to be apart of Super Bowl LVIII at Super Bowl Opening Night. 11-year-old reporter Jeremiah Fennell and NFL Network's Michael Robinson ...

Depending on where a fan's allegiances lie, there may be no better follow-up in the aftermath of Super Bowl LVIII ... 49ers players if they really thought that was going to be enough to win the game.

As all 13 teams that were shut out in the first half in Super Bowl history went on to lose the game ... and San Francisco 49ers had a low scoring first half in Super Bowl LVIII.

The sky is falling in the Bay Area, but the San Francisco 49ers finally got some good and 'potentially significant' news. Per ...

As the weather turns colder and the leaves turn brown, it can only mean one thing: NFL football means just a little bit more.

The Kansas City Chiefs will play a rare Friday game in Week 13, hosting the Las Vegas Raiders for a special Black Friday edition of the NFL.

The Packers are eager to parry their own jab after last year's playoff exit at the hands of what's become a familiar foe.

John Lynch explained how he and the San Francisco 49ers are "inspired" by Dre Greenlaw's return from his Achillies tear.