From a broader perspective, it will be imperative to find out why cytokine signalling promotes replicative and oncogene-induced senescence, but does not seem to induce senescence in every ...

In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...

We want to know, for example, does a keratinocyte undergoing replicative senescence secrete a similar type of inflammatory molecule as a fibroblast undergoing senescence induced by ultraviolet ...