San Francisco 49ers quarterback and Iowa State alum Brock Purdy is showing promising signs after being injured on Nov. 17.

All-Pro linebacker Matt Milano and breakout rookie receiver Keon Coleman both practiced for the Bills on Wednesday. Milano ...

San Francisco 49ers head coach Kyle Shanahan told reporters that star quarterback Brock Purdy will practice with the team ...

Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth Lombardi Trophy. The Niners have made four NFC Championship Game appearances ...

Buffalo Bills quarterback Josh Allen and coach Sean McDermott reacted to forecasts of a snow game against the San Francisco ...

The San Francisco 49ers fell to an incomprehensible 5-6 with their Week 12 loss to the Green Bay Packers, and while the 49ers ...

Don’t even bring up the possibility of 49ers coach Kyle Shanahan being fired around wide receiver Deebo Samuel. Despite San ...

San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there ...

Former San Francisco 49ers player and coach Tommy Hart has passed away at the age of 80. Hart, a multi-time Super Bowl ...

Could the San Francisco 49ers sign Daniel Jones after a rough loss in Week 12? One NFL insider says it's a 'very real' ...

In the San Francisco 49ers Week 14 contest against the Chicago Bears, the team will wear their customized cleats on the field ...

The San Francisco 49ers may again be without starting quarterback Brock Purdy for their Week 13 clash with the San Francisco ...