Quench Bio has emerged from stealth mode with $50 million of committed funding, bidding to be the first company to target Gasdermin D (GSDMD) in inflammatory disease indications poorly served by ...

Caspase 1 also cleaves the protein gasdermin-D, which then forms pores in a cell’s membrane, often causing a type of cell death known as pyroptosis. In 2015, in collaboration with The University ...